Are you passionate about protein engineering, directed evolution, and green chemistry? This PhD project at Vrije Universiteit Amsterdam (VU) could be your perfect platform to dive into the emerging world of non-canonical amino acids. Join a cutting-edge team exploring novel enzymes that push the boundaries of biocatalysis—from pharmaceuticals to sustainable materials.
🔬 What’s the Focus?
In this project, you’ll harness the potential of non-canonical amino acids to design enzymes with:
- Enhanced catalytic performance
- Greater stability under diverse conditions
- Entirely new functionalities not found in nature
You’ll work with state-of-the-art tools in protein engineering, molecular biology, and analytical techniques (e.g., HPLC, MS, NMR). The ultimate goal is to showcase how these expanded building blocks can revolutionize biocatalysis for greener, more efficient chemical processes.
🌱 Why VU Amsterdam?
- Interdisciplinary Research Hub: Collaborate with chemists, biochemists, and molecular biologists at the cutting edge of enzyme design.
- Advanced Facilities: Access top-tier labs equipped with modern instrumentation for directed evolution, protein purification, and analytical chemistry.
- Personal Growth: Take part in teaching assignments, hone communication skills, and forge an international network.
- Live in Amsterdam: Experience the cultural, academic, and social highlights of a dynamic European city.
🎓 Key Qualifications
- Master’s degree in Biochemistry, Chemistry, Molecular Biology, or a related field.
- Experience in molecular biology (cloning, mutagenesis, protein expression/purification).
- Familiarity with analytical methods like HPLC, NMR, MS, or spectroscopy.
- Knowledge of chemical synthesis and catalysis is beneficial.
- Fluent in English, both written and spoken.
Even if you don’t match every requirement, but feel you can excel, you’re encouraged to apply.
📋 Position Details
- Contract: Full-time, temporary (initially 1 year; extension up to 4 years).
- Salary: From €2,901 (1st year) up to €3,707 (4th year) gross/month.
- Timeline: Project start between July and November 2025.
- Additional perks include 8% holiday allowance, 8.3% year-end bonus, commuting expense contributions, and more.
📝 How to Apply
Prepare:
- Detailed CV
- Motivation Letter: Why a PhD in enzyme design? Why at VU?
- Academic Records (Bachelor’s + Master’s transcripts)
- Reference Contacts (at least 2)
Apply Online by March 31, 2025, via AcademicTransfer.com. Incomplete applications or those sent by email will not be considered.
🌐 Contact
- Project Inquiries: Dr. Ivana Drienovska (i.drienovska@vu.nl)
VU Amsterdam seeks to foster a diverse and inclusive environment. Applications from underrepresented groups are greatly welcomed.
Leap into Next-Generation Biocatalysis!
If you’re eager to expand the genetic code and engineer enzymes with unparalleled capabilities, this PhD position offers you the chance to do groundbreaking research in a collaborative, innovative setting. Apply now and help redefine the future of green chemistry!
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