If you’re passionate about understanding the molecular principles of protein folding and eager to contribute to groundbreaking research, here’s an incredible opportunity for you! The Protein Biogenesis Lab at the prestigious Francis Crick Institute in London is seeking a Postdoctoral Fellow to join their dynamic team.
About the Lab
Led by Dr. Balchin, the Protein Biogenesis Lab explores how the cellular environment influences protein folding pathways. Established in 2020, the team includes 3 postdocs, 3 PhD students, and 2 research scientists. The lab thrives on a supportive and collaborative research culture, valuing collegiality and open scientific discussions.
Their research focuses on key questions in protein folding, such as:
- How do nascent and stress-denatured proteins behave in vivo?
- What roles do molecular chaperones play during co-translational folding?
- How are defective proteins identified and directed to quality control machinery?
- What governs substrate recognition by molecular chaperones?
About the Role
As a Postdoctoral Fellow, you’ll have the opportunity to:
- Lead research on protein folding and assembly in bacteria and human cells.
- Dive into the interplay between protein synthesis, molecular chaperones, and quality control mechanisms.
- Utilize cutting-edge methods like:
- Cryo-electron microscopy (cryo-EM)
- Proteomics
- Biochemical reconstitution
- Mass spectrometry
- Fluorescence microscopy
Projects will be tailored to your expertise and interests, allowing you to make a significant impact in the field.
What They’re Looking For
Essential Qualifications:
- A PhD in a relevant field, awarded or nearing completion.
- Experience in protein biochemistry and mechanistic studies of protein folding or molecular chaperones.
- Strong publication track record showcasing your expertise.
Desirable Skills:
- Expertise in protein folding, molecular chaperones, or ribosomes.
- Familiarity with advanced techniques like hydrogen/deuterium exchange and cryo-EM.
Why Work at The Francis Crick Institute?
Working at the Crick means being part of a world-class research environment that fosters creativity and collaboration. You’ll enjoy:
- Generous leave: 28 days of annual leave, plus Christmas and bank holidays.
- Comprehensive benefits: Including pension contributions (up to 16%), health services, and childcare support.
- Diversity and inclusion: A workplace that celebrates and supports people of all backgrounds.
- Development opportunities: Access to mentoring, training, and career growth resources.
The institute also provides visa support for international candidates, ensuring you can focus on your research.
How to Apply
Interested candidates should submit their application by February 28, 2025. For more details about the role and team, visit the Protein Biogenesis Lab page or contact nicola.gyte@crick.ac.uk for assistance with your application.
A Word About The Francis Crick Institute
Located in the heart of London, the Francis Crick Institute is renowned for its innovative approach to biomedical research. They are bold, open, and collegial, creating an environment where scientists thrive and collaborate on impactful discoveries.
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Disclaimer: This information is accurate as of the date of posting. Please refer to the official website for the most current details.