Are you a passionate researcher looking to advance your career in proteomics? The University of Liverpool is inviting applications for a Postdoctoral Research Associate in Proteomics to join their prestigious Health and Life Sciences Faculty. This full-time, fixed-term position offers the opportunity to work on cutting-edge research in the Department of Biochemistry, Cell and Systems Biology, contributing to an ambitious and multidisciplinary project.
The Role and Project Overview
As a Postdoctoral Research Associate, you will play a key role in the recently awarded BBSRC Strategic Longer and Larger project (sLoLa), GlycoWeb, which aims to unravel the biology of glycosaminoglycans (GAGs). These biomolecules, present on nearly all cell surfaces and in the extracellular matrix, are vital for processes like cell signaling, development, and host-pathogen interactions. Despite their importance, the mechanisms regulating GAG biosynthesis and their structural-functional relationships remain poorly understood.
The GlycoWeb project is a collaborative effort involving leading institutions, including the Universities of Liverpool, Nottingham, Manchester, and the Francis Crick Institute, along with international partners in Denmark and the USA, and commercial collaborations with InterReality Labs. The project employs advanced proteomics, transcriptomics, and cutting-edge technologies like virtual reality to address these fundamental knowledge gaps.
What You’ll Be Doing
As part of this team, you will:
- Lead quantitative mass spectrometry-based proteomics experiments, focusing on post-translational modifications (PTMs) like phosphorylation.
- Analyze experimental data using statistical and pathway interrogation methods to uncover insights into GAG biosynthesis and function.
- Collaborate with national and international research partners, with potential opportunities for travel.
- Contribute to high-impact publications and present findings at conferences and team meetings.
- Play an active role in mentoring students and junior researchers within the group.
- Work in the Centre for Proteome Research (CPR), equipped with 11 state-of-the-art mass spectrometers, offering advanced capabilities such as top-down proteomics and native MS.
Your Profile
Essential Skills and Experience
- Proven expertise in mass spectrometry-based proteomics, demonstrated through publications in leading journals.
- Hands-on experience in sample preparation, data analysis, and statistical interpretation for quantitative proteomics.
- Deep understanding of PTMs and their roles in protein biochemistry and cell signaling.
- Excellent interpersonal and organizational skills, with the ability to work independently and within a team.
Desirable Skills
- Advanced knowledge of phosphopeptide analysis and bioinformatics tools.
- Experience with high-performance liquid chromatography (HPLC) or mass spectrometry instrumentation maintenance.
- Strong scientific writing and presentation skills, with a history of oral presentations at international meetings.
Why Join the University of Liverpool?
The University of Liverpool is a Russell Group institution, internationally recognized for excellence in research and teaching. As part of the Institute of Systems, Molecular and Integrative Biology, you’ll benefit from a supportive and collaborative environment that values innovation and diversity.
Key Benefits:
- Competitive salary: £39,105 – £45,163 per annum.
- Access to outstanding research facilities and resources.
- Opportunities for professional development and career advancement.
- The chance to contribute to impactful research addressing global health challenges.
Application Process
How to Apply:
To apply, set up an account on the University of Liverpool’s Vacancies Portal and submit your application. Once submitted, you’ll receive an email confirmation. If you do not hear back within six weeks of the closing date, consider your application unsuccessful.
Right to Work:
Applicants must have the legal right to work in the UK. Assistance with visa applications and relocation support is available.
Contact Information:
For further details, reach out to Professor Claire Eyers at ceyers@liverpool.ac.uk.
Final Thoughts
This position offers a unique opportunity to work at the intersection of proteomics and cutting-edge biological research. By joining the University of Liverpool, you’ll contribute to groundbreaking discoveries that could transform our understanding of GAGs and their role in health and disease. Whether you’re an experienced researcher or a newly minted PhD, this role provides the platform to make a significant impact while advancing your scientific career.
Ready to take the next step? Apply today and join a vibrant community of researchers making a difference!
Connect with Us
If these positions resonate with your career goals, we encourage you to apply or share this opportunity with your network.
Stay updated with the latest career opportunities in life sciences, engineering, and technology by following our Facebook page or bookmarking BioCareersHub.com.
Together, let’s build a future where innovation meets impact!
